Introduction: Cutaneous Leishmaniasis is considered as an important health problem in Iran. This disease begins as small swells (papules) and then they gradually grow and turn into wounds. Since the epidemiological study of this problem is effective in preventing and controlling it, the current research was conducted to study the epidemiological study of cutaneous Leishmaniasis in Khash city during the past 7 years.

Methods: This cross-sectional study has been conducted on registered information and documents of the patients having problem in Khash city’s remedial and health care centers over the past 7 years. First, the registered demographic and epidemiological data of the patients were extracted and then they were analyzed by using SPSS 18 software with chi-square test .

Results: 175 patients included 88 males (53%) and 87 females (47%). The majority of the patients were between nine months and four years old and the minority of them were over the range of 40 to 49 years old. Most lesions were on the face or organs of the patients. It was also found that there was a significant relationship between age groups and types of Leishmaniasis (P<0.05) as well as gender and type leishmaniasis (P<0.05).

Conclusion: According to our study, there has been a downward trend in disease frequency in Khash city from 2009 to 2014. This reduction of the disease is due to an improvement in health education situation as well as performance of personal hygiene tasks among the people.