Volume 14, Number 4 (Pajouhan Scientific Journal, Summer 2016)                   psj 2016, 14(4): 18-26 | Back to browse issues page



DOI: 10.21859/psj-140418

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Gholami A, Arabestani M R, Ahmadi M. Evaluation of antibacterial activity of aqueous and methanol extracts of Allium Jesdianum plant on a number of pathogenic bacteria resistant to antibiotics. psj. 2016; 14 (4) :18-26
URL: http://psj.umsha.ac.ir/article-1-202-en.html

1- MSc in Microbiology, Faculty of Medicine, Student Research Center, Hamadan University of Medical Sciences, Hamadan, Iran
2- Assistant Professor, Department of Microbiology, Brucellosis Research Center, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran , mohammad.arabestani@gmail.com
3- BSc in Microbiology, Reaserch Center for Molucular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
Abstract:   (1510 Views)

Introduction: Considering growing increase of antibacterial resistance to antibiotics and existing of anti-bacterial compounds in plants, in this study the antibacterial effect of aqueous and methanol extracts of Allium jesdianum plant on some species of pathogenic bacteria was evaluated.

Methods: In this experimental study, the aqueous and methanol extracts of Allium jesdianum plant were prepared from Allium jesdianum plant. The antimicrobial effects of the extracts were evaluated by two methods: broth microdilution and agar-well diffusion on the bacteria in comparison with Gentamicin. The data were analysed by two independent samples T-test (SPSS-16).

Results: The methanol extracts had a significant antibacterial eeffect on all examined Gram-positive and gram negative bacteria, except for Enterococcus faecalis (P<0.05). The largest inhibitory diameter (12 mm) of growth was seen in Streptococcus pyogenes and Pseudomonas aeruginosa strains and MIC for these two strains was obtained at 16 mg/L. The aqueous extract of the leaves of this plant had an effect on all examined bacteria except Enterococcus faecalis isolates except for Enterococcus faecalis (P<0.05). Also, the aqueous extract influenced better than other methanol extracts (P<0.05).

Conclusion: According to the results of this study and increasing resistance of bacteria to chemical antibiotics, it is recommended that more studies on this plant as an antibacterial compound are needed for treating bacterial infections.

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Type of Study: Research Article | Subject: Basic Sciences
Received: 2016/03/7 | Accepted: 2016/05/24 | Published: 2016/07/28

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