Volume 17, Issue 1 (Pajouhan Scientific Journal, Autumn 2018)
Pajouhan Sci J 2018, 17(1): 23-29 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Faradmal J, Ramazanjammat S, Bayat M, Karimi N, Roshanaei G, Mazdeh M. Demographic and Clinical Characteristics of Guillain-Barre Syndrome (GBS) in Patients Referring to Farshchian Hospital of Hamadan during 2006- 2015. Pajouhan Sci J 2018; 17 (1) :23-29
URL: http://psj.umsha.ac.ir/article-1-423-en.html
URL: http://psj.umsha.ac.ir/article-1-423-en.html
Javad Faradmal1 
, Sara Ramazanjammat2 , Molood Bayat3 , Nasim Karimi2 , Ghodratollah Roshanaei * 4, Mehrdokht Mazdeh5
, Sara Ramazanjammat2 , Molood Bayat3 , Nasim Karimi2 , Ghodratollah Roshanaei * 4, Mehrdokht Mazdeh5
1- PhD of Biostatistics, Modeling of Noncommunicable Diseases Research Center, Department of Biostatistics and Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran
2- Ms of Biostatistics, student research center, Hamadan University of Medical Sciences, Hamadan, Iran
3- Ms of nursing, student research center, Hamadan University of Medical Sciences, Hamadan, Iran
4- PhD of Biostatistics, Modeling of Noncommunicable Diseases Research Center, Department of Biostatistics and Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran , gh.roshanaei@umsha.ac.ir
5- Research Center for Behavioral Disorders and Substances Abuse, Hamadan University of Medical Sciences, Hamadan, Iran
2- Ms of Biostatistics, student research center, Hamadan University of Medical Sciences, Hamadan, Iran
3- Ms of nursing, student research center, Hamadan University of Medical Sciences, Hamadan, Iran
4- PhD of Biostatistics, Modeling of Noncommunicable Diseases Research Center, Department of Biostatistics and Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran , gh.roshanaei@umsha.ac.ir
5- Research Center for Behavioral Disorders and Substances Abuse, Hamadan University of Medical Sciences, Hamadan, Iran
Abstract: (4682 Views)
Background and Objective: Guillain-Barre syndrome is an autoimmune neurological disease that is considered as the most serious type of paralysis without reflex. Different factors and therapeutic measures are effective in causes and how to control it. The aim of this study was to determine the epidemiology of Guilen Barre syndrome in Hamedan province during the years 2006-2015.
Materials and Methods: In this cross-sectional descriptive study the required information from the records of 159 patients admitted to hospital Farshchian Hamadan, was investigated over a period of 8 years. The relationship between variables was analyzed by SPSS software version 16 using chi-squared test and independent T-test.
Results: Of the 159 patients, 58 (40.8%) were female and 98 (61.6%) were married. The mean age of patients was 48 ± 22.6. Lower limb weakness (95%) was the most common symptom and difficulty in swallowing and respiratory distress had the lowest incidence of symptoms. The largest age group of patients with Guillen-Baar syndrome was between the ages of 21-30. Relative healing was observed in 43 cases (27%) and death was observed in 15 cases (9.4%). There was no statistically significant relationship between gender, age, and marital status with symptoms appearing in patients with Guillen-Baar syndrome.
Conclusion: The results revealed a different pattern of the epidemiology of Guillain-Barre syndrome in Iran from other countries. So different environmental factors are involved in GBS. According to disability and even death in such GBS patients, further research to find the etiology, treatment and prevention services will be required.
Materials and Methods: In this cross-sectional descriptive study the required information from the records of 159 patients admitted to hospital Farshchian Hamadan, was investigated over a period of 8 years. The relationship between variables was analyzed by SPSS software version 16 using chi-squared test and independent T-test.
Results: Of the 159 patients, 58 (40.8%) were female and 98 (61.6%) were married. The mean age of patients was 48 ± 22.6. Lower limb weakness (95%) was the most common symptom and difficulty in swallowing and respiratory distress had the lowest incidence of symptoms. The largest age group of patients with Guillen-Baar syndrome was between the ages of 21-30. Relative healing was observed in 43 cases (27%) and death was observed in 15 cases (9.4%). There was no statistically significant relationship between gender, age, and marital status with symptoms appearing in patients with Guillen-Baar syndrome.
Conclusion: The results revealed a different pattern of the epidemiology of Guillain-Barre syndrome in Iran from other countries. So different environmental factors are involved in GBS. According to disability and even death in such GBS patients, further research to find the etiology, treatment and prevention services will be required.
Type of Study: Research Article |
Subject:
Biostatistic & Epidemiology
Received: 2018/01/31 | Accepted: 2018/08/21 | Published: 2018/11/15
Received: 2018/01/31 | Accepted: 2018/08/21 | Published: 2018/11/15
References
1. Mazaheri S, Rezaie A, Hosseinzadeh A. The ten years survey on clinical and epidemiologic features of guillian-barre syndrome in sina hospital, Hamadan, Iran. Journal of Research in health sciences. 2005;14(244:(56-60. (Persian) [DOI]
2. Rahimi jaberi A, Manafi A, Mossallaiepoor A, Ebrahimi M M, Khazforoosh S, Shirazi zade mehraban S, et al . The Epidemiologic, Clinical and Laboratory Findings of Patients with Guillain Barre´ Syndrome in Southern Iran Since 2007 to 2012. J Fasa Univ Med Sci. 2014; 3 (4) :343-347. (Persian) [DOI]
3. Esteghamati A, Gouya MM, Keshtkar AA, Mahoney F. Relationship between occurrence of Guillain-Barre syndrome and mass campaign of measles and rubella immunization in Iranian 5–14 years old children. Vaccine. 2008;26(39):5058-61. [DOI]
4. Rocha MS, Brucki SM, Carvalho A, Lima UW. Epidemiologic features of Guillain-Barre syndrome in Sao Paulo, Brazil. Arquivos de neuro-psiquiatria. 2004;62(1):33-7. [DOI]
5. Tekgul H, Serdaroglu G, Tutuncuoglu S. Outcome of axonal and demyelinating forms of Guillain-Barré syndrome in children. Pediatric Neurology. 2003;28(4):295-9. [DOI]
6. Farhoudi M, Ayromlou H, Bazzazi AM, Shadi FB, Golzari S, Ghabili K, et al. Time frequency of Guillain-Barre syndrome in northwest of Iran. Life Sci J. 2013;10(1):223-5. [DOI]
7. Clinical and Laboratory Features of Childhood Guillain-Barre Syndrome Associated with Campylibacter Jejuni Infection. Pajoohandeh. 2010;14(6):307-12. (Persian) [DOI]
8. Barzegar M, Farid SD, Dastgiri S, Malekian A, Toopchizadeh V. Childhood Guillian-barre syndromme in the iran east azerbaijan province: 2001-2005. Iranian Journal of Child Neurology. 2008;2(4):25-31. [DOI]
9. Baxter R, Bakshi N, Fireman B, Lewis E, Ray P, Vellozzi C, et al. Lack of association of Guillain-Barré syndrome with vaccinations. Clinical infectious diseases. 2013;57(2):197-204. [DOI]
10. Huda MN, Khan MM, Azam B, Uddin MJ. Study of Cerebrospinal Fluid (CSF) and Clinical and Electrophysiological Features of Hospitalized Patients with Gullain-Barre´ Syndrome. Journal of Enam Medical College. 2015;5(3):145-50. [DOI]
11. Arami MA, Yazdchi M, Khandaghi R. Epidemiology and characteristics of Guillain-Barre syndrome in the northwest of Iran. Annals of Saudi medicine. 2006;26(1):22. [DOI]
12. Sejvar JJ, Baughman AL, Wise M, Morgan OW. Population incidence of Guillain-Barré syndrome: a systematic review and meta-analysis. Neuroepidemiology. 2011;36(2):123-33. [DOI]
13. Xiong CH, Liao Z, Peng SH, Wen HR, Zhang YX, Chen SH, et al. Epidemiologic Characteristics of Guillain-Barre Syndrome in Nanchang China: a Retrospective Study. International Medical Journal. 2014;21(5):496-499. [DOI]
14. Rocha MSG, Brucki SMD, Carvalho AA, Lima ÚWP. Epidemiologic features of guillain-barré syndrome in São Paulo, Brazil. Arquivos de neuro-psiquiatria. 2004;62(1):33-7. [DOI]
15. Wakerley BR, Uncini A, Yuki N; GBS Classification Group. Guillain–Barré and Miller Fisher syndromes – new diagnostic classification". Nature Reviews Neurology.2014, 10 (9): 537–44. [DOI]
16. 16. Shahrizaila, N, Yuki N. Bickerstaff brainstem encephalitis and Fisher syndrome: anti-GQ1b antibody syndrome. Journal of Neurology, Neurosurgery & Psychiatry. 2012, 84 (5): 576–583. [DOI]
17. Blum S, Reddel S, Spies J, McCombe P. Clinical features of patients with Guillain‐Barré syndrome at seven hospitals on the East Coast of Australia. Journal of the Peripheral Nervous System. 2013;18(4):316-20. [DOI]
18. Ruiz E, Ramalle-Gómara E, Quiñones C, Martínez-Ochoa E. Trends in Guillain–Barré syndrome mortality in Spain from 1999 to 2013, International Journal of Neuroscience, 126:11, 985-988. [DOI]
19. Chaudhuri JR, Alladi S, Mridula KR, Boddu DB, Rao M, Hemanth C, et al. Clinical outcome of Guillain-Barré syndrome with various treatment methods and cost effectiveness: A study from tertiary care center in South India: Yashoda GBS Registry. Neurology Asia 2014; 19(3): 263 – 270 [DOI]
20. Anthony S, Fauci, Braunwald E, Kasper DL. Harrison`s Principles of Internal Medicine. 18th ed, New York: McGrawHill; 2012. 1783-8. [DOI]
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
Articles Copyright © The Author(s).
Owned by Hamadan University of Medical Sciences.
Published by UMSHA Press
Journal Tel: +98 81 38380090
Publisher Tel: +98 81 38382022
Website: https://psj.umsha.ac.ir/
Email: psj@umsha.ac.ir
