1 1029-7863 Hamadan University of Medical Sciences 107 Basic Sciences The use of nanoparticles in diagnosis and treatment of breast cancer: A review Salehzadeh Maryam b Norouzian Parham c Abbasalipourkabir Roghayeh d b Student of Dentistry, Tehran University of Medical Sciences, Tehran, Iran c Student of Pharmacy, Students Research Center, Hamadan University of Medical Sciences, Hamadan, Iran d Assistant Professor of Biochemistry, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran 1 3 2015 13 2 1 12 14 10 2014 30 01 2015 Introduction: Nowadays, cancer is one of the most important health concerns in modern societies. The application of nanoparticles has resulted in new possibilities for the diagnosis, tumor imaging and treatment of human cancers. Methods: Gathering and collecting of data have been done from 56 researches conducted on the structure of types of nanoparticles and their applications in diagnostics, imaging and drug delivery systems for the treatment of cancer. Results: The inorganic nanoparticles such as quantum dots, which have a central core of magnetic properties, can be used for the detection and imaging of tumors, as well as the organic nanoparticle systems such as liposomes, solid lipid nanoparticles, aptamers, dendrimers and nanobody in different drug-ligands. Aptamers are the oligonucleotids or peptides that bind to the protein or certain targets. Various applications of aptamers include diagnostics, therapeutics, molecular imaging and drug delivery. Moreover, nanobodies are of antibody like molecules which are widely used in the diagnosis and treatment of cancer. Conclusion: Although there are some challenges and limitations on the use of nanoparticles in medicine, it is hoped that in the near future, nanoparticles create tremendous revolutionary not only in the oncology but also in medicine. The current paper is an overview of the application of organic and inorganic nanoparticles in diagnosis and treatment of the neoplasm.
112 Medicine & Clinical Sciences Investigation of pediculosis prevalence and associated factors in the central prison of Hamadan in 2013 Nazari Mansour e Goudarztalejerdi Reza f Moradi Abbas g e Associate Professor of Medical Entomology, Hamadan University of Medical Sciences, Hamadan, Iran f MSc of Medical Entomology, Students Research Center, Hamadan University of Medical Sciences, Hamadan, Iran g Instructor of Epidemiology, Dept. of Social Medicine, Hamadan University of Medical Sciences, Hamadan, Iran 1 3 2015 13 2 13 20 04 10 2014 30 01 2015 Introduction: Despite progress in health and medical sciences, human lice are still considered as a health problem. The aim of this study was to investigate the prevalence and factors associated with its pediculosis in Central Prison of Hamadan in 2013. Methods: In this descriptive and analytical cross sectional study, from 2900 male prisoners, 384 were selected by the systematic method. After reviewing in terms of pediculosis infection, the extracted data were analyzed by using SPSS software version 20. Results: The study showed that 5.2% of the prisoner was infected with louse. Most infections were observed in the age group of 30-39 years old, and the lowest in the group of 20 years old and less (P>0.05). The highest rate of pediculosis was seen in the people had drug addiction, and buying and selling, no specific bed, common use of bed and blankets, bath once and less per week (P0.05). Most cases of infected with lice were in the head (85%), body (10%) and pubic (5%). Conclusion: Considering the results of this study, it can be said that the conditions of the prison, including density, the type of crime and lack of hygiene and the use of personal devices are highly associated with the prevalence of pediculosis. 131 Medicine & Clinical Sciences Quality of compliance of patient’s rights in operating rooms of Hamadan’s educational hospitals in 2012 Zandiyeh Mitra h Pakro Payravandi Akram i Imani Behzad j Ahmadi Sara k Roshanaei Ghodratollah l h Department of Operating Room, School of Para Medicine, Hamadan, University of Medical Sciences, Hamadan, Iran i Student of Operating Room, Students Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. j Department of Operating Room, School of Para Medicine, Hamadan University of Medical Sciences, Hamadan, Iran k Student of Operating Room, Bualicina Hospital, Hamadan University of Medical Sciences, Hamadan, Iran l Modeling of Noncommunicable Diseases Research Center, Department of Biostatistics and Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran 1 3 2015 13 2 21 31 11 08 2014 15 01 2015 Introduction: Quality care and client satisfaction are of major priority in health services. Compliance of patient rights causes their satisfaction therefore, it is one of health care preferences and unavoidable necessities. Considering this issue and importance of quality control of cares, this study was accomplished in order to determine quality of performance of patient’s rights by surgical and anesthesia staff at Hamadan’s educational hospitals in 2012. Methods: This descriptive analytic research was conducted on all surgical and anesthesia staff as well as operating room of the educational hospitals (205 people). Required information was gathered through four checklists of the performance of patient’s rights in different sections including reception, surgery room (surgical and anesthesia staff) and recovery. Each one of the staff was observed five times. In order to analyze the data, SPSS software version 16 and chi-square test were used. Results: Mean score of patient’s rights compliance in reception, surgical and anesthesia staff, and recovery sections were, respectively, 70 , 56.3 , 57 and 55 of total score of the pertinent checklists. Patient’s rights compliance in all parts were in moderate level (50.2 ), and had significant relation with sex (P=0.03) and part (P=0.01). Conclusion: The performance of patient’s rights in operating room of Hamadan educational hospitals was average in 2012. Based on the results, appropriate measures should be performed in aspects of introduction of HCWs, selection of anesthetic technique, giving necessary information, respect to patient privacy and obtaining specific surgical consent. 137 Psychology and Psychiatry The relation between life expectancy and early maladaptive schemas in the mothers of children with intellectual disability in Kermanshah City in 2014 Yavari Abdolreza m Sorouri Faranak n Rezaei Mohammad o Weisi Farzad p Tahmasebi Bahram m MSc in Speech Therapy, Faculty of Rehabilitation Sciences, Arak University of Medical Sciences, Arak, Iran n MSc in General Psychology, Psychology Department, Azad University of Tonekabon, Tonekabon, Iran o MSc in Speech Therapy, Faculty of Rehabilitation Sciences, Hamadan University of Medical Sciences, Hamadan, Iran p Ph.D. Student of Speech Therapy, Faculty of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran MSc in General Psychology, Faculty of Rehabilitation Sciences, Hamadan University of Medical Sciences, Hamadan, Iran 1 3 2015 13 2 32 39 11 11 2014 30 01 2015 Introduction: Expectancy acts as a basis for dealing with problems in human. Early schemas are beliefs that people have about themselves and others and environment and generally stem from not satisfying basic essentials, particularly emotional needs, in childhood. The aim of this study was to determine relationship between life expectancy and early maladaptive schemas in the mothers of children with intellectual disability and also the relation between life expectancy and each determined schema was investigated. Methods: This descriptive, analytical, cross-sectional study was performed on 50 mothers, who were selected through available sampling referring to rehabilitation centers of Kermanshah City in 2014, with intellectual disabled children in. The questionnaires of life expectancy and early maladaptive schemas were used for data gathering. The information obtained was analyzed by regression analysis through SPSS version 22. Results: The results of regression analysis showed significant relationship between social isolation scheme (P= 0.002), impaired limits schema (P= 0.007) and other-directedness schema (P= 0.003) with life expectancy in mothers of children with intellectual disability. There was not significant relationship between other schemas and life expectancy. Conclusion: There is a significant relationship between other-directedness schema and impaired limits and social isolation schemas in the mothers of children with intellectual disability and life expectancy. Indeed, the more sensible are these schemas, the more life expectancy is projected for the mothers. Thus, these schemas can be used to enhance the life expectancy of the mothers of children with intellectual disability. 136 Rehabilitation Study of verb tense inflection evaluating methods and determination of the best methodin 3 or 4 year-old children in Rasht City in 2014 Khoshhal Zeynab Shirazi Sahere Sima Mahmoodi Bakhtiari Behruz Bakhshi Enayatolla MSc of Speech Therapy, Department of Speech Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Ph.D. of Speech Therapy, Department of Speech Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Associate Professor of Linguistics, Department of Performing Arts, University of Tehran, Tehran, Iran Assistant Professor of Biostatistics, Department of Statistics, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 1 3 2015 13 2 40 49 30 06 2014 24 12 2014 Introduction: one domain of morphology is inflection that adds syntactic considerations to the words. This domain is affected in individual with language disorders. So evaluation of inflection in these people is important. In this study, methods of verb tense inflection evaluation were compared and the best method was determined. Methods: This study was descriptive-analytical. The participants included 27 girls and 28 boys who were in age group 3 and 4 years old. They were selected by multistage sampling method of Rasht kindergartens. 8 tasks were used for evaluating of verb tense inflection, include: Two optional task, Question task, Sentence completion 1, Sentence completion 2, Immediate repetition, Modelling 1, Modeling 2, Story completion. The tenses that were evaluated included: past simple, present perfect, past continuous, past perfect, simple present, present subjunctive. The results of study were analyzed using central tendency include the mean, measures of variability include the standard deviation (or variance), the minimum and maximum values of the variables and repeated measures with the use of SPSS 16. Results: The mean scores of immediate repetition was more than others but because of inefficiency was abandoned. Thus story completion was chosen as the best method. Also the results of repeated measures showed that the scores of other methods had significant difference with story completion. Modeling 1 and modeling 2 had the least scores. Conclusion: The story completion is the best method among other methods of this study. 145 Medicine & Clinical Sciences The effect of using logbook on emergency medical srvices student’s satisfaction and clinical evaluation, in Hamadan University of Medical Sciences in 2013 Karampourian Arezo Khatiban Mahnaz Jahanghiri Katayuon Razavi Zahra Imani Behzad Hamadan, Iran Hamadan University of Medical Sciences, Hamadan, Iran Tehran, Iran Hamadan, Iran Hamadan University of Medical Sciences, Hamadan, Iran 1 3 2015 13 2 50 56 04 10 2014 30 01 2015 Introduction: Evaluation is the most sufficient approach to improve the quality of education. In order to reach this goal, there have been many tools that one of them is logbook. Present study aims to estimate the effect of using logbook on students’ satisfaction and clinical evaluation in Hamadan University of Medical Sciences in 2013. Methods: In this interventional study, 33 students were involved. The assessment content and face validity of the statistical forms and the questionnaire were approved by the members of the faculty. Cronbach’s alpha coefficient was obtained 97.0 for forms and 91.0 for questionnaires. The results were compared. Data was analyzed by SPSS 16 with T-test and Pearson correlation coefficient. Results: Mean score of students’ satisfaction from evaluation by logbook was 2.55±0.62, mean score of students’ self-evaluation was 2.96±1.03, evaluation score of first instructor was 2.81±1.03, evaluation score of the second instructor was 2.74±1.01and also evaluation score of both instructors was 2.77±1.01. The results showed significant correlation between students’ self-evaluation scores and evaluation scores of both instructors, between students’ satisfaction and their mean self-evaluation scores, between students’ self-evaluation and evaluation score of both instructors and students’ academic marks. However there was a significant inverse correlation, between student’s satisfaction and evaluation score of both instructors (P<0.05). Conclusion: According to the students’ satisfaction of using logbook and the same scores of self-assessment between students and teachers, one can suggest this approach in clinical education owing to its effectiveness, objectiveness and acceptability. 132 Medicine & Clinical Sciences Patients’ satisfaction with the implementation of clinical governance in surgery ward of the Besat Hospital of Hamadan in 2013 Imani Behzad Abolfathi Zahra Hamadan, Iran Students Research Center, Hamadan Universtiy of Medical Sciences, Hamadan, Iran 1 3 2015 13 2 57 62 13 12 2014 30 01 2015 Introduction: In order to improve the quality of provided services in hospitals, implementation of clinical governance depends on a number of factors, including: things which cause decreased or increased patients’ satisfaction, effect of staff’s treatment on patients’ satisfaction and participation of staff in the project. The aim of this study was to determine patients’ satisfaction with the implementation of clinical governance in surgery ward of Besat Hospital of Hamadan in 2013. Methods: This cross-sectional study was performed on 122 patients admitted to the hospital to undergo surgery in Besat hospital. Patients were selected based on random sampling. The data gathering tool was a researcher-made two-part questionnaire. After completing the questionnaire, patients’ data was analyzed using descriptive statistics and by SPSS version 17 software. Results: 64% of patients have never been admitted to the mentioned hospital before, and habitation place of 64% of patients was in the city and 36% in rural area. also most of the patients 45% were under diploma. The results showed that patients were grouped as 2% without satisfaction, 11% less satisfied, 55% moderately satisfied and 32% very satisfied. Conclusion: The results showed that suitable treatment of hospital staff, responding to patients’ questions, informing patients’ of their disease, as well as to explain the current status, all lead to increased patients’ satisfaction, cooperation with medical staff and therefore promoting the process of healing and treatment of disease.