Mohammad Kazem Sabzehei, Asadolah Tanasan , Yones Mohammadi , Soroush Taheri Talesh, Maryam Zeinali,
Volume 19, Issue 1 (Pajouhan Scientific Journal, Autumn 2020)
Abstract
Background and Objective: The Patent Ductus Arteriosus (PDA) occurs in 50% of infants under 1000 g and 30% of infants less than 1500 g. Treatment failure can exacerbate respiratory distress and its complications. Acetaminophen is a new drug with fewer side effects. The present study was designed and performed to evaluate the effect of this drug and intravenous ibuprofen on the treatment of Patent Ductus Arteriosus.
Materials and Methods: In this case-control study, 50 preterm infants who were less or equal to 14 days of age and diagnosis of PDA by echocardiographic were included and randomly divided into two groups. The first group was treated with intravenous ibuprofen and the second group was treated with intravenous acetaminophen for three days. At the end, the necessary information, including echocardiographic findings were analyzed using SPSS software version 16.
Results: The findings of the present study showed that both ibuprofen and acetaminophen had equal effect in the closing of PDA in preterm infants. There was no significant difference in the duration of hospitalisation between two groups (P = 0.259). Possible side effects include intra-ventricular hemorrhage, thrombocytopenia, serum creatinine greater than 1.5 mg / dl, decreased urinary volume, necrotizing enterocolitis, positive blood culture and bronchopulmonary dysplasia were not significantly different between the two groups. The only significant complication was gastrointestinal bleeding, which was almost equally prevalent in both groups.
Conclusion: Acetaminophen such as ibuprofen is effective as the main treatment of patent ductus arteriosus (PDA) and it could be a safe alternative to ibuprofen.
Mr Milad Hajighafoori-Boukani, Mr Arash Khalili, Dr Asadolah Tanasan, Dr Leili Tapak, Tayebeh Hasan Tehrani,
Volume 20, Issue 3 (Pajouhan Scientific Journal, Summer 2022)
Abstract
Background and Objectives: Congenital heart disease is one of the most common congenital anomalies in children. The purpose of this study was the evaluation of social support in parents of children with congenital heart disease.
Materials and Methods: This was a descriptive correlational study. The study population included 200 parents of children with congenital heart disease who referred to Imam Khomeini Clinic in Hamedan in 2020 via available sampling method and using the demographic information questionnaire, social support questionnaire Zimat. Data was analyzed using descriptive and inferential statistics.
Results: The mean and standard deviation of the total score of social support 41.4 ± 5.61. The highest social support 15.71 ± 2.23 was related to the family dimension and the lowest social support 12.17 ± 2.39 was related to the dimension of friends. The results of this study showed that the average total score of social support in terms of all demographic variables of parents except maternal occupation has a statistically significant difference (P < 0.05).
Conclusions: Social support is tool that improves the quality of life in parents of children with congenital heart disease, so it is recommended to develop a comprehensive care plan for these patients alongside, increasing their parent's social support.
