Introduction: Spouse abuse refers to any violent behavior dependent on gender and resulting in physical, sexual, psychological injuries and women suffering. It has adverse consequences in society and family. Current study was aimed to assess factors affecting spouse abuse in women in Shiraz city.

Methods: This descriptive, analytical, cross-sectional study was conducted on women victims of spouse abuse referring to center of legal medicine of Shiraz city, 197 patients were randomly selected in 2013. The data were collected using a demographic information form, a standard questionnaire assessing violence against women, general health questionnaire, and Female Sexual Function Index. The data were analyzed by the SPSS version 18 statistical software using, Pearson’s correlation coefficient and regression.

Results: Among the highest rates of spouse abuse, psychological violence, with an average (55.80) and the lowest economic violence with an average of (6.11), respectively. There was a significant and direct correlation between in dimensions of physical violence (P=0.001; r: 0.10), economic violence (P=0.007; r: 0.15) and general violence (P=0.052; r: 0.11) and the general sexual function. Moreover, the variables of contraception, family involvement spouse, history of husband addiction, number of children, economic class of parents spouses, spouse age and sexual function significantly predicted the spouse abuse in women (P<0.05).

Conclusion: Due to the high prevalence of domestic violence and its relationship with the couple’s characteristics, increase awareness of the problem and the factors influencing it, seems necessary.