Introduction: Injuries from accidents are the major and avoidable causes of illness and death in most countries of the world. Knowledge of the occurrence of accidents is of special importance to health policy makers. The aim of this study was to determine the injuries caused by accidents in emergency department of Hamadan province.

Methods: This study is descriptive-analytic from cross sectional type, that all patients referred to emergency department of hospitals in Hamadan province, during 2009 to 2014, were assessed. Data extracted from injury register software and was analyzed with Stata software version 12, at an inaccuracy of less than 5%.To determine the relation between sex and mechanism of injury chi square test was used.

Results: A total of 135,925 patients were registered during this period. Mean age of patients was 30.19±18.4. 72.6% of cases were men and 39.74% in the age group of 20-34 years. Household accidents included 37.27% of the occurred accidents. Hitting (22.21%), car accidents (21.78%) and falling (10.69%), were the most accidents accounted in both sexes. There was a significant difference between sex and mechanism of injury (P<0.001).

Conclusion: Because the men in youth and middle age are the most victims of accidents, therefore a great economic burden is imposed on the society. Moreover, it is necessary to allocate precise educations for this age group and to take preventive strategies to reduce the burden of injuries related to accidents.